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A New Mutation Resulting in the Truncation of the TRAF6-Interacting Domain of XEDAR: A Possible Novel Cause of Hypohidrotic Ectodermal Dysplasia

research A New Mutation Resulting in the Truncation of the TRAF6-Interacting Domain of XEDAR: A Possible Novel Cause of Hypohidrotic Ectodermal Dysplasia

17 citations , August 2012 in “Journal of Medical Genetics”

A new mutation in the XEDAR gene might cause a rare skin condition called hypohidrotic ectodermal dysplasia.

research XEDAR Activates the Non-Canonical NF-κB Pathway

18 citations , August 2015 in “Biochemical and Biophysical Research Communications”

XEDAR triggers a specific signaling pathway in cells.

research Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases

6 citations , August 2022 in “International Journal of Molecular Sciences”

EDA signaling is linked to skin disorders, various cancers, and liver disease.

research Edar Signaling in the Control of Hair Follicle Development

71 citations , November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

Edar signaling is crucial for proper hair follicle development and function.

research Myodegeneration in EDA-A2 Transgenic Mice Is Prevented by XEDAR Deficiency

75 citations , January 2004 in “Molecular and Cellular Biology”

XEDAR deficiency prevents muscle degeneration in EDA-A2 transgenic mice.

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