144 citations
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August 2019 in “Cells” This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.
27 citations
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April 2017 in “Journal of Investigative Dermatology” The researchers reported that noncoding double-stranded RNA promotes wound-induced hair neogenesis in mice by modulating prostaglandin and Wnt levels.
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study revealed that telocytes are crucial Wnt-producing niche cells necessary for hair follicle regeneration in mice, with their removal or the absence of their Wnt signals halting the regenerative process.
10 citations
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November 2018 in “Nature Biotechnology” Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
3 citations
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November 2015 in “Journal of Investigative Dermatology” This study examines the interaction between androgen receptor signaling and the β-catenin/Wnt signaling pathway in mouse hair follicles, but reports no clinical results.