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research In Vivo Uptake and Metabolism of Testosterone by the Skin and Other Tissues of the Rat

8 citations, May 1982 in “Journal of Endocrinology/Journal of endocrinology”

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

research Is The Metabolism Of Testosterone To 5α-Dihydrotestosterone Required For Androgen Action In The Skin?

14 citations, November 1982 in “British Journal of Dermatology”

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

research Species Differences in Prostatic Steroid 5α-Reductases of Rat, Dog, and Human

193 citations, August 1985 in “Endocrinology”

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor

86 citations, March 1993 in “Toxicology and Applied Pharmacology”

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

research External Genitalia Abnormalities in Male Rats Exposed In Utero to Finasteride, a 5α-Reductase Inhibitor

122 citations, July 1990 in “Teratology”

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

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community Long term finasteride users; Did you notice any improvement after 2 years?

in Finasteride/Dutasteride 14 upvotes 1 year ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community abusing caffeine boosts DHT levels!

in Research/Science 1 upvotes 2 months ago

Caffeine intake may increase DHT levels, but its impact on hair loss is minimal compared to genetic factors. Excessive caffeine can cause health issues, and its effects on hair loss are not directly applicable to humans based on rat studies.