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    GlossaryAlopecia Universalis

    complete loss of all body and scalp hair

    Alopecia Universalis (AU) is a severe form of alopecia areata characterized by the complete loss of hair on the scalp and body, including eyebrows and eyelashes. It is an autoimmune condition where the immune system mistakenly attacks hair follicles, leading to total hair loss.

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      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community No hair, don't care! [24/F] :)

       59 upvotes 9 years ago
      A woman with alopecia universalis shares her positive experience of being bald, finding it freeing and less worrisome. She also discusses her skincare routine using Korean products.

      community Alopecia Areata Question

      in Treatment  2 upvotes 4 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community Hairloss all over body and head

      in Treatment  2 upvotes 6 days ago
      A 25-year-old experiencing hair thinning all over the body and head, despite using minoxidil and having low vitamin D levels, is advised to seek a second opinion from a dermatologist specializing in hair loss. The likely diagnosis is diffuse alopecia areata, which may require treatment with a JAK inhibitor.

      community Why Is No One Talking About Chromosome 20?

      in Chat  32 upvotes 4 months ago
      Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.