21 citations
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May 2014 in “Toxicological Sciences” Toluene diisocyanate exposure can cause immune sensitization by interacting with proteins in hair follicles and sebaceous glands.
17 citations
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October 2012 in “European Journal of Pharmacology” This study investigated the effects of acute toluene inhalation on core body temperature in mice, focusing on the involvement of GABAA and GABAB receptors and neurosteroids. Toluene exposure at concentrations of 4000 and 6000 ppm resulted in a concentration-dependent decrease in core temperature. The hypothermic effect at 4000 ppm was mitigated by GABAA receptor blockers (picrotoxin, bicuculline), a GABAB receptor antagonist (phaclofen), and a neurosteroid synthesis inhibitor (finasteride), but not by the benzodiazepine receptor antagonist flumazenil. However, none of these treatments prevented the hypothermic effect at 6000 ppm, suggesting different mechanisms of action at higher concentrations.
47 citations
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June 2015 in “Contact Dermatitis” A standardized patch test for hair cosmetics is needed in Europe to prevent allergies, especially for hairdressers.
16 citations
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October 2009 in “Xenobiotica” The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.
January 1993 in “Side effects of drugs annual” Natural products like propolis are causing more skin allergies, and certain skin treatments and medications have various side effects and risks.