Search
for

    GlossaryThin-Layer Chromatography (TLC)

    Thin-Layer Chromatography (TLC) is a laboratory technique used to separate and identify compounds in a mixture. It involves applying a small sample to a thin layer of adsorbent material (like silica gel) coated on a glass or plastic plate. The plate is then placed in a solvent, which moves up the layer by capillary action, carrying different compounds at different rates based on their interactions with the adsorbent and the solvent. This method is widely used for analyzing the components of complex mixtures, such as in drug testing, food safety, and biochemical research.

    Related Terms

    Learn

    0 / 0 results
    — no results

    Research

    5 / 349 results

    Community Join

    5 / 77 results
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 6 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
      Shedding or receding even more?

      community Shedding or receding even more?

      in Journals / Progress Pictures  159 upvotes 2 days ago
      The user experienced hair shedding after using finasteride and topical minoxidil since August 2024, and briefly adding oral minoxidil in early 2025. They suspect the shedding might be due to the oral minoxidil, a bad batch of finasteride, or a normal shedding cycle, and are also experiencing an itchy scalp and acne.
      1 year on fin, before and after

      community 1 year on fin, before and after

      in General  31 upvotes 1 week ago
      The user has been using finasteride three times a week for a year and plans to add minoxidil to improve hair regrowth. They are seeking opinions on any noticeable new hair growth.