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Tyrosine Kinase Inhibitors

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research Comparison of Pemetrexed and Docetaxel as Salvage Chemotherapy for the Treatment of Non-Small-Cell Lung Cancer After the Failure of Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors

12 citations, January 2014 in “Journal of international medical research”

Pemetrexed is as effective as docetaxel but has fewer side effects for treating nonsmall-cell lung cancer after EGFR-TKI therapy failure.

research Tyrosine Kinase Inhibitors: A Review on Pharmacology, Metabolism, and Side Effects

508 citations, June 2009 in “Current drug metabolism”

Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.

research The PDGF/PDGFR Pathway as a Drug Target

182 citations, November 2017 in “Molecular Aspects of Medicine”

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

research Unique Cutaneous Reaction to Second- and Third-Generation Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia

32 citations, September 2015 in “Dermatology”

Certain leukemia drugs can cause severe skin reactions that may require stopping treatment.

Clinical Management of Cutaneous Adverse Events in Patients on Targeted Anticancer Therapies and Immunotherapies: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology

research Clinical Management of Cutaneous Adverse Events in Patients on Targeted Anticancer Therapies and Immunotherapies: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology

26 citations, October 2018 in “Clinical & Translational Oncology”

Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.

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community Minox experimentation on pubic hair

in Minoxidil 280 upvotes 9 months ago

A user applied minoxidil to their pubic hair for 3 months, resulting in hair growth over 4 inches, and is considering using it for a scalp hair transplant. They plan to continue the treatment despite their wife's disapproval.

community Anyone else’s beard took a huge hit on finasteride or dutasteride? Would minoxidl hepl?

in Progress Pictures 105 upvotes 1 year ago

The effects of finasteride and dutasteride on beard growth, whether minoxidil would help with facial hair loss caused by DHT blockers, and anecdotal evidence from users who have experienced either decreased or increased facial hair density while using these treatments.