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GlossaryTeratogenicity (Teratogenesis)

ability of a substance to cause birth defects

Teratogenicity refers to the ability of a substance to cause birth defects or developmental malformations in a developing embryo or fetus. This can occur when a pregnant woman is exposed to certain drugs, chemicals, or environmental factors that interfere with normal fetal development, potentially leading to physical or functional abnormalities in the newborn.

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research Fetal Alcohol Syndrome: Current Status of Pathogenesis

171 citations , October 1990 in “Alcoholism/Alcoholism, clinical and experimental research”

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

research Use of Chemotherapy During Human Pregnancy

724 citations , April 2004 in “Lancet Oncology”

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1

research American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1

343 citations , October 2015 in “Endocrine Practice”

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

research Molecular Epidemiology of Hypospadias: Review of Genetic and Environmental Risk Factors

103 citations , October 2003 in “Birth Defects Research”

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

research Adverse Effects of Common Medications on Male Fertility

77 citations , June 2015 in “Nature Reviews Urology”

Some common medications can harm male fertility, but many effects can be reversed.

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community Male (24) Using Dutasteride Since 2020 – Concerns About Having Kids

in Finasteride/Dutasteride 90 upvotes 11 months ago

A 24-year-old male using dutasteride for hair loss is worried about its effects on fertility and future children's health. Users advise consulting a doctor, possibly switching to finasteride, or stopping dutasteride before conception due to its impact on sperm count.