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    GlossaryTricyclic Antidepressants (TCAs)

    medications that treat depression by increasing certain brain neurotransmitters

    Tricyclic Antidepressants (TCAs) are a class of medications primarily used to treat depression. They work by increasing the levels of certain neurotransmitters, such as serotonin and norepinephrine, in the brain, which helps improve mood. TCAs are also sometimes prescribed for chronic pain, anxiety disorders, and certain types of headaches. While effective, they can have significant side effects, including dry mouth, weight gain, and dizziness, which is why they are often not the first choice of treatment.

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