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GlossaryErlotinib (Tarceva)

medication that inhibits cancer cell growth by targeting EGFR

Erlotinib is a medication used to treat certain types of cancer, such as non-small cell lung cancer and pancreatic cancer. It works by inhibiting the epidermal growth factor receptor (EGFR), which is involved in the growth and spread of cancer cells. By blocking this receptor, erlotinib can help slow down or stop the progression of the disease.

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research Tyrosine Kinase Inhibitors: A Review on Pharmacology, Metabolism, and Side Effects

508 citations, June 2009 in “Current drug metabolism”

Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.

research Trichomegaly of the Eyelashes After Treatment with Erlotinib in Non-Small Cell Lung Cancer

12 citations, November 2006 in “Journal of thoracic oncology”

A cancer patient's eyelashes grew excessively without other common side effects after taking the cancer drug erlotinib.

research Are All Adverse Effects Undesirable? A Case of Chemotherapy-Induced Adverse Effect - An Exception!

October 2021 in “International journal of basic and clinical pharmacology”

Excessive eyelash growth from erlotinib may indicate positive tumor response and help treat madarosis.

research Flecainide

August 2011 in “Reactions Weekly”

A man with lung cancer had skin and eye side effects from erlotinib but continued treatment with symptom improvement.

Cutaneous and Mucosal Side Effects of New Anticancer Drugs: EGF-R Inhibitors, Tyrosine Kinase Inhibitors, and Mitotic Spindle Stabilizers

research Cutaneous and Mucosal Side Effects of New Anticancer Drugs: EGF-R Inhibitors, Tyrosine Kinase Inhibitors, and Mitotic Spindle Stabilizers

January 2011

New cancer drugs can cause skin side effects like rashes, dry skin, hair changes, and nail problems.

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