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GlossaryErlotinib (Tarceva)

medication that inhibits cancer cell growth by targeting EGFR

Erlotinib is a medication used to treat certain types of cancer, such as non-small cell lung cancer and pancreatic cancer. It works by inhibiting the epidermal growth factor receptor (EGFR), which is involved in the growth and spread of cancer cells. By blocking this receptor, erlotinib can help slow down or stop the progression of the disease.

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research Abstract 4350: Pharmacodynamic Biomarkers: Evaluation of Oncology Drug Target Engagement in Human Plucked Scalp and Beard Hair

April 2023 in “Cancer Research”

Plucked hair can effectively monitor drug effects in cancer treatment.

research Tyrosine Kinase Inhibitors: A Review on Pharmacology, Metabolism, and Side Effects

508 citations , June 2009 in “Current drug metabolism”

Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.

research A Case of Cicatricial Alopecia Associated with Erlotinib

25 citations , January 2011 in “Annals of Dermatology”

Erlotinib can cause hair loss as a side effect.

Trichomegaly of the Eyelashes After Treatment with Erlotinib in Non-Small Cell Lung Cancer

research Trichomegaly of the Eyelashes After Treatment with Erlotinib in Non-Small Cell Lung Cancer

12 citations , November 2006 in “Journal of thoracic oncology”

A cancer patient's eyelashes grew excessively without other common side effects after taking the cancer drug erlotinib.

Scalp Pustule as a Manifestation of Erlotinib-Induced Skin Toxicity: Report of Two Cases and Literature Review

research Scalp Pustule as a Manifestation of Erlotinib-Induced Skin Toxicity: Report of Two Cases and Literature Review

1 citations , April 2025 in “Clinical Cosmetic and Investigational Dermatology”

Erlotinib can cause scalp pustules and hair loss, needing early treatment with antibiotics and steroids.

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