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Research

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research Decision letter: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage

June 2021

This study found that chronic UVR exposure in mice and humans leads to a permanent loss of papillary fibroblasts in the upper dermis, which is associated with changes in the extracellular matrix.

research Effects of Visible Light on the Skin^†

195 citations , January 2008 in “Photochemistry and Photobiology”

This review discusses the effects of visible light on human skin, highlighting its role in pigmentation, thermal damage, and the treatment of several skin conditions, while noting limited sunscreen protection against it; no new clinical results are reported.

research 458 UVB-induced facultative pigmentation is associated with distinct DNA methylation changes

November 2025 in “Journal of Investigative Dermatology”

This study found that UVB exposure led to visible tanning and distinct DNA methylation changes in pigmentation genes in tan-capable skin but not in non-tan skin, highlighting GNAS as a potentially UVB-responsive gene.

research Differences in cell subsets between sun-exposed and unexposed skin: preliminary single-cell sequencing and biological analysis from a single case

3 citations , October 2024 in “Frontiers in Medicine”

This study investigated single-cell changes in photoaged skin, revealing distinct cell clusters and increased activity in PD-L1 and PD-1 pathways in sun-exposed areas, enhancing understanding of UVA-induced skin damage and potential prevention targets for photoaging and UV-induced skin cancers.

research HPV8 Field Cancerization in a Transgenic Mouse Model Is due to Lrig1+ Keratinocyte Stem Cell Expansion

25 citations , June 2017 in “Journal of Investigative Dermatology”

This study found that in a transgenic mouse model, β-HPV infection led to increased skin thickness and proliferation of specific keratinocyte stem cells, which may contribute to squamous cell carcinoma development.

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Community Join

5 / 424 results

community Going bald is a genuine health issue.

100 upvotes 1 month ago

Bald people have a higher risk of skin cancer, especially on the scalp, and wearing a hat is suggested as a solution. Hair loss treatments like Minoxidil, finasteride, and RU58841 are not mentioned in this conversation.

community The Health Benefits of Head Hair

in Research/Science 19 upvotes 11 months ago

Hair provides protection against head trauma, reduces skin cancer risk, helps remove heavy metals, and aids in wound healing. The conversation emphasizes the health benefits of maintaining head hair beyond cosmetic reasons.

community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 1 year ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 64 upvotes 2 years ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

community Could male-pattern baldness have a secondary photobiological function? The Solar Window Hypothesis

11 upvotes 1 month ago

Male-pattern baldness might increase UVB exposure on the scalp, potentially affecting vitamin D and skeletal health. The hypothesis is debated, with some seeing it as a minor benefit in specific contexts.

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Learn

2 / 2 results

learn Hair Transplant

When can I go in the sun after a hair transplant? Avoid direct sun exposure for at least 2 to 6 weeks after a hair transplant.

learn Scalp Micropigmentation

Can I go in the sun after scalp micropigmentation? Avoid direct sun exposure for 2 to 4 weeks after scalp micropigmentation.

Clinics

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All 13 clinic results →

Experts

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Hair Transplant Surgeon
Dr. Sun Zhengwu, MD
Malmö, Sweden

Dr. Sun Zhengwu, MD