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research Effets secondaires cutanéo-muqueux des nouvelles molécules anticancéreuses: Inhibiteurs de l'EGF-R, inhibiteurs de tyrosine kinase et stabilisateurs du fuseau mitotique

January 2011

This article discusses the various skin side effects associated with targeted cancer therapies like tyrosine kinase inhibitors and EGF-R inhibitors but provides no new clinical findings.

research Advances in the Management of Cutaneous Toxicities of Targeted Therapies

42 citations , April 2012 in “Seminars in Oncology”

This review discusses the skin side effects associated with targeted cancer therapies and reports no new clinical results; it emphasizes the need for empirical management based on expert opinion.

research Hand-Foot and Stump Syndrome to Sorafenib

45 citations , January 2007 in “Journal of Clinical Oncology”

This case report identifies hand-foot and stump syndrome as a potential side effect of sorafenib therapy in a 47-year-old man with a leg amputation.

research Acne inversa-like lesions associated with the multi-kinase inhibitor sorafenib

11 citations , December 2013 in “Clinical and Experimental Dermatology”

This article reviews the use of sorafenib, a multikinase inhibitor, for treating certain carcinomas, noting that cutaneous toxicity during treatment may indicate successful antitumor activity; however, it reports no new clinical results.

research Tyrosine Kinase Inhibitors – A Review on Pharmacology, Metabolism and Side Effects

508 citations , June 2009 in “Current drug metabolism”

This review details the skin and hematological toxicities of tyrosine kinase inhibitors like erlotinib, gefitinib, and imatinib, and highlights ongoing concerns about cardiac toxicity, reporting no new clinical findings.

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community Sublingual Minoxidil - Cure to Hairloss?

in Minoxidil 583 upvotes 3 years ago

The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

community For sublingual minoxidil users and topical minoxidil drinkers : You should STOP spraying topical minoxidil to your mouth NOW. You should consider stopping using a drop of it and mixing it with some other substance too, as you may mess up the dosage

in Minoxidil 183 upvotes 10 months ago

Spraying or drinking topical minoxidil is dangerous and less effective than oral minoxidil. Proper oral minoxidil, like Loniten®, is recommended for safety and effectiveness.

community [M31] 2+ years progress on Oral Dutasteride and Sublingual Minoxidil

in Progress Pictures 67 upvotes 2 years ago

A user shared their 2+ years progress on Oral Dutasteride and Sublingual Minoxidil for hair loss. Another user asked about the form of Minoxidil used sublingually.

community Diluting Melatonin Sublingual Spray

in Treatment 2 upvotes 2 years ago

A user wants to dilute a melatonin sublingual spray to 0.0033% for use as a topical hair loss treatment. They ask if distilled water can be used for dilution and how much is needed for stability over months.

community After about 3 months of 2mg Estradiol (Sublingual) and 2.5mg Minox (Oral) daily

in Progress Pictures 160 upvotes 10 months ago

A person transitioning is using 2mg sublingual estradiol and 2.5mg oral minoxidil daily for hair regrowth, noting significant progress in three months. They plan to increase estrogen dosage and consider adding dutasteride, discussing the effects and challenges of transitioning.

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