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GlossarySpirochete

spiral-shaped bacteria known for their corkscrew motion

Spirochetes are a group of spiral-shaped bacteria known for their unique corkscrew motion, which allows them to move through viscous environments like mucus. They are responsible for several significant diseases in humans, including Lyme disease (caused by *Borrelia burgdorferi*) and syphilis (caused by *Treponema pallidum*).

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research Syphilitic Alopecia: Report of a Challenging Case and Review of the Literature

December 2020 in “Journal of clinical and investigative dermatology”

A man with syphilitic alopecia and neurosyphilis was successfully treated with penicillin, leading to symptom improvement and resolution of hair loss.

research The RpoS Gatekeeper in Borrelia Burgdorferi: An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity

91 citations , August 2019 in “Frontiers in Microbiology”

RpoS helps Borrelia burgdorferi survive in hosts and adapt to different environments.

research A Complete Guide to Human Microbiomes: Body Niches, Transmission, Development, Dysbiosis, and Restoration

72 citations , July 2022 in “Frontiers in Systems Biology”

Modern lifestyles harm beneficial microbes, affecting health.

research Phenolsulphotransferase: Localization in Kidney During Human Embryonic and Fetal Development

18 citations , November 1994 in “Histochemical Journal”

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas

68 citations , September 2003 in “British Journal of Dermatology”

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

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