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Ligand-Dependent Wnt Signaling Attenuates Mechanotransduction and Protects Against Wound Occlusion-Mediated Abolishment of Hair Follicle Regeneration

research Ligand-Dependent Wnt Signaling Attenuates Mechanotransduction and Protects Against Wound Occlusion-Mediated Abolishment of Hair Follicle Regeneration

April 2023 in “Journal of Investigative Dermatology”

Covering a wound can stop hair growth by promoting scarring, but boosting a process called Wnt signaling can help hair grow back even when the wound is covered.

research Ligand-Dependent Wnt Signaling Attenuates Mechanotransduction and Protects Against Wound Occlusion-Mediated Abolishment of Hair Follicle Regeneration

May 2023

research Wnt Signaling Modulates Mechanotransduction in the Epidermis to Drive Hair Follicle Regeneration

February 2025 in “Science Advances”

Wnt signaling helps regenerate hair follicles by affecting how skin cells sense and respond to mechanical forces.

research Ex Vivo SIM-AFM Measurements Reveal the Spatial Correlation of Stiffness and Molecular Distributions in 3D Living Tissue

October 2024 in “Acta Biomaterialia”

Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.

research Biomaterials for In Situ Tissue Regeneration: Development and Perspectives

79 citations, January 2015 in “Journal of Materials Chemistry B”

Smart biomaterials that guide tissue repair are key for future medical treatments.

View more "spatial rigidity gradient" in research →

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community Are Derma Rollers Actually Harmful in the Long Run?

in Microneedling 40 upvotes 2 months ago

Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

community Kintor has announced the results for their human Phase I trials of GT20029

in Research/Science 256 upvotes 2 years ago

The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.