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research Management of Cutaneous and Extracutaneous Side Effects of Smoothened Inhibitor Therapy for Advanced Basal Cell Carcinoma

16 citations, March 2015 in “Clinical Cancer Research”

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

research Oncogenes and Morphogens: Intricacies of Targeted Therapy in Cutaneous Basal Cell Carcinoma

December 2017 in “British Journal of Dermatology”

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

Smoothened Receptor Inhibitor Vismodegib for the Treatment of Basal Cell Carcinoma: A Retrospective Analysis of Efficacy and Side Effects

research Smoothened Receptor Inhibitor Vismodegib for the Treatment of Basal Cell Carcinoma: A Retrospective Analysis of Efficacy and Side Effects

8 citations, May 2019 in “Journal of dermatological treatment”

Vismodegib is effective for basal cell carcinoma but has severe side effects.

research Targeting Smoothened for Therapeutic Gain

105 citations, April 2014 in “Trends in Pharmacological Sciences”

Targeting the Smoothened receptor shows promise for treating certain cancers.

research Alopecia in Association with Malignancy: A Review

26 citations, August 2018 in “American Journal of Clinical Dermatology”

Hair loss in cancer patients can be related to the cancer itself, treatment, or other conditions, and understanding it is important for diagnosis and patient care.

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community It's over. Hairline has fallen. Millions must shave.

in Update 467 upvotes 1 year ago

The conclusion of the conversation is that the user has tried various medications and treatments for hair loss, including minoxidil, finasteride, microneedling, and nizoral shampoo, but has not seen any progress. They have decided to shave their head. Other users suggest options such as hair transplants, RU58841, hair units, and scalp micropigmentation.

community Ultimate DHT/finasteride microdosing graph to replace the commonly one referenced on forums

in Finasteride/Dutasteride 204 upvotes 3 years ago

Hair loss treatments, specifically, discussing the effectiveness and side effects of finasteride, minoxidil, and RU58841 in various microdoses. It also includes an updated graph which provides information on how different doses affect DHT levels, scalp skin and serum androgen levels, as well as hair count.

community Why isnt topical fin talked about more?

in Chat 43 upvotes 1 week ago

Topical finasteride is less popular due to inconvenience, cost, and availability, while oral finasteride is favored for ease and safety. Some users experience side effects with topical use, but find it effective with minoxidil, though opinions on its efficacy vary.

community 5 months oralfin, topmin, dermarolling

in Progress Pictures 856 upvotes 1 year ago

The user "ninezske" shared their progress pictures of hair regrowth after using oral finasteride, topical minoxidil, and dermarolling. Other users commented on the results and discussed the effectiveness of minoxidil and finasteride.

community Hairline Progress 24M - 4 month report. 5% min 1x/day, 1mg Fin every other day, 0.5mm microneedle 1x/week. Biotin and multivitamins too. Pretty stoked with the results!

in Progress Pictures 88 upvotes 2 years ago

A 24-year-old man shared his 4-month hair regrowth progress using 5% Minoxidil once daily, 1mg Finasteride every other day, weekly 0.5mm microneedling, Biotin, and multivitamins. Commenters suggest adding Tretinoin could enhance results, while others express happiness for his improvement.