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research Anti-SARS-CoV-2 Action of 5α-Reductase Inhibitors May Be Mediated by Dehydroepiandrosterone

1 citations, February 2022 in “The Journal of Urology”

Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

research Neurosteroids, Neuroactive Steroids, and Symptoms of Affective Disorders

82 citations, August 2006 in “Pharmacology, Biochemistry and Behavior”

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

research Neuroactive Gonadal Drugs for Neuroprotection in Male and Female Models of Parkinson's Disease

34 citations, December 2015 in “Neuroscience & Biobehavioral Reviews”

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction

research 5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction

26 citations, September 2018 in “Neurobiology of Disease”

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

research The 5-Alpha Reductase Inhibitor Finasteride Reduces Dyskinesia in a Rat Model of Parkinson’s Disease

15 citations, January 2017 in “Experimental Neurology”

Finasteride reduces movement issues in Parkinson's disease rats.

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community 18M progression pt.3 (6 months)

in Progress Pictures 744 upvotes 1 year ago

User started balding at 16 and began treatment at 18, using RU58841, minoxidil, derma rolling, and peptides. After 6 months, they experienced significant hair regrowth and are happy with the results.

community 21M with a nasty case of MPB; Heres what's on my radar for the future.

in Research/Science 16 upvotes 2 years ago

Hopeful treatments for hair loss, including Verteporfin, Androgen Receptor Degradation, and SCUBE3. These treatments offer potential solutions to slow or stop the effects of androgens on the scalp.

community To all the young non-responders out there

in Update 119 upvotes 1 year ago

A 21 year old who has been taking various treatments for hair loss such as dutasteride, RU58841, minoxidil and finasteride with no results. Other users share their experiences of dealing with hair loss at an early age and offer advice on how to cope.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 127 upvotes 4 months ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community I enjoy taking finasteride every day

in Finasteride/Dutasteride 241 upvotes 6 months ago

Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

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