11 citations
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May 2010 in “Journal of Medicinal Chemistry” This study introduced a novel nonsteroidal androgen receptor antagonist that effectively controls sebum production in the golden Syrian hamster ear model through targeted follicular delivery.
14 citations
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December 2013 in “Experimental Dermatology” The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, mouse sebaceous glands were found to require nerves for growth during active hair cycles, suggesting a nerve-dependent sebaceous gland cycle coordinated with hair growth.
44 citations
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January 2013 in “BMC Dermatology” This study found that TGFβ signaling is essential for keeping sebocytes undifferentiated by reducing lipid-related gene expression, using a novel human sebocyte culture model.
This article reviews the effects of combined oral contraceptives on skin conditions and suggests prescribing guidelines for women with acne, as it reports no new clinical results.