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research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery
A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
research Regional difference in sebum production by androgen susceptibility in human facial skin
The T-zone on the face has more androgen receptors and produces more oil than the U-zone.
research 574 Murine sebaceous gland homeostasis requires intact cutaneous innervation in a hair cycle-dependent context
Mouse skin glands need healthy nerves to grow properly during hair growth phases.
research TGFβ signaling regulates lipogenesis in human sebaceous glands cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
research Effect of contraceptives on the skin.
COCs can improve acne but may cause skin issues like cholasma; high estrogen is advised for hair loss concerns.
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5 / 102 resultscommunity possible treatment of AGA and change in sebaceous gland condition and oil production using sulfur soap
Sulfur soap may help with hair thickening and reducing scalp inflammation, but it can cause dryness. Nizoral, containing ketoconazole, is noted for its potential to reduce seborrheic dermatitis but may also cause scalp dryness and hair loss.
community Finasteride gives me seb derm. Thoughts on zinc or other options?
A user with diffuse hair loss after taking accutane, which might have triggered genetic predisposition to AGA; their experience taking finasteride and experiencing side effects of increased oil production, increased sex drive, worsening hair texture; they are considering zinc supplementation with finasteride or other treatments such as alfatradiol or spironolactone.
community Why does Finasteride make my hair not get greasy fast anymore?
Finasteride, a hair loss treatment, was observed to reduce scalp oiliness in users. Anti-androgens like Finasteride are known to decrease the activity of oil-producing glands.
community DHT Harms Scalp Microbiome: DHT Itch is REAL
Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.
community Double Shampooing Everyday. Safe or not?
Double shampooing daily is safe and helps manage oily scalp and dandruff without causing hair loss. Accutane is considered for reducing sebum production despite potential temporary hair loss.