research HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro
This study demonstrated that culturing high-passage dermal papilla cells with specific supplemented conditioned media may preserve their hair-inducing abilities, suggesting potential for reconstructing new hair follicles in vivo.