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research C2orf37 mutational spectrum in Woodhouse–Sakati syndrome patients

43 citations , April 2010 in “Clinical genetics”

This study identified four novel mutations in the C2orf37 gene among Woodhouse–Sakati syndrome patients, doubling known mutations, and found no significant link between isolated symptoms like deafness and dystonia and these mutations.

research Endocrine disorders in Woodhouse-Sakati syndrome: a systematic review of the literature

31 citations , January 2014 in “Journal of endocrinological investigation”

This study reviewed Woodhouse-Sakati syndrome and found it consistently associated with hypogonadism, decreased IGF1, and frontotemporal alopecia, with additional symptoms like intellectual disabilities and diabetes in some patients.

research Expanding on the phenotypic spectrum of Woodhouse‐Sakati syndrome due to founder pathogenic variant in DCAF17: Report of 58 additional patients from Qatar and literature review

10 citations , September 2021 in “American Journal of Medical Genetics Part A”

This study on Qatari patients with Woodhouse-Sakati syndrome highlights the high incidence and diverse clinical presentation due to a specific genetic variant, emphasizing early diagnosis for effective management.

The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome

research The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome

7 citations , January 2015 in “Case reports in genetics”

This case report illustrates how SNP array testing helped identify a DCAF17 mutation linked to Woodhouse-Sakati syndrome in consanguineous Qatari siblings with shared features including alopecia and hypogonadotropic hypogonadism.

Woodhouse-Sakati Syndrome: A Case Study of Three Saudi Sisters

research Woodhouse-Sakati syndrome (WSS)

5 citations , November 2021 in “Saudi medical journal”

This report describes three Saudi sisters with Woodhouse-Sakati syndrome, who exhibited typical features of the condition along with unusual gynecological anomalies.

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Community Join

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community Oh my god for fucks sake why does creatine cause hair loss.. why can't no one possiblly come with why it causes hair loss

in Research/Science 7 months ago

Creatine is debated for causing hair loss, with some users claiming it raises DHT levels, while others argue it has no significant effect. Despite conflicting opinions, some users report hair loss even when using DHT blockers like finasteride.

community STOP LYING FOR LORD'S SAKE because you're misleading people who are trying their best

in Chat 185 upvotes 1 year ago

Some users believe people falsely claim hair restoration results from finasteride and minoxidil alone, while actually having hair transplants. Finasteride and minoxidil, often used with microneedling and nizoral, are effective for many, but results and opinions on dosages vary.

community Don't discount diet for the sake of scalp health. Meds had no effect for 2+ years. 3.5 months since new diet / Shampoo routine.

in Progress Pictures 300 upvotes 2 years ago

Diet and specific shampoo improved scalp health and hair regrowth for someone with seborrheic dermatitis, while medications like Minoxidil and finasteride had no effect. A low-sugar, keto diet was key to their success.

community Forget about new treatments (just temporarily for the sake of argument). What do you think is the likelihood of existing treatments being improved in the next few years?

1 upvotes 1 year ago

Existing hair loss treatments like oral finasteride, topical minoxidil, and hair transplants are still the main options, with some improvements in affordability and techniques. There is hope for enhancing these treatments, but new effective solutions are unlikely in the near future.

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Learn

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learn Hair Transplant

Are there any risks associated with beard transplantation? Beard transplantation carries risks of infection, scarring, swelling, and uneven growth.
Does a beard transplant hurt? A beard transplant is mostly painless due to local anesthesia, with mild soreness possible afterward.
How long does a beard transplant take? A beard transplant typically takes 3 to 8 hours to complete.
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learn Scalp Micropigmentation

Can scalp micropigmentation hide my scars? Scalp micropigmentation can significantly reduce the visibility of scars on the scalp.

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