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Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/- Mice

research Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/- Mice

8 citations, March 2014 in “American Journal of Pathology”

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

research Traumatic Anserine Folliculosis: A Cause of Facial Follicular Papules

August 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

Rubbing or pressing on the face can cause small bumps, and changing posture along with certain creams can improve them.

research The Effects of Gamma Rays on the Regeneration of Hair Follicles Are Carried Over to Later Hair Cycles

5 citations, November 2015 in “International Journal of Radiation Biology”

Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.

research Effects of Gamma Rays on the Regeneration of Murine Hair Follicles in the Natural Hair Cycle

3 citations, June 2017 in “International Journal of Radiation Biology”

Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.

research Hair Morphogenesis In Vitro: Formation of Hair Structures Suitable for Implantation

43 citations, August 2008 in “Regenerative Medicine”

Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.

View more "rudimentary hair follicles" in research →

Community Join

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community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 97 upvotes 5 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 137 upvotes 8 months ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community Let's talk about natural options and last resorts.

in Chat 7 upvotes 11 months ago

The user discusses their long struggle with hair loss, considering various treatments like hair transplants, hair systems, and natural methods such as micro-needling, vitamin supplements, and a healthy lifestyle. They express concerns about side effects from drugs like finasteride and ultimately lean towards using a hair system for better appearance and confidence.

community Is RU558841 actually related to heart issues?

in Finasteride/Dutasteride 11 upvotes 1 month ago

RU58841 may cause heart-related side effects like palpitations and chest pain, though evidence is mostly anecdotal. Users report mixed experiences, with some stopping due to side effects and others using it without issues, but concerns about its safety and sourcing remain.