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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

Insulin resistance is found in 20% of Thai women with PCOS, with age, waist size, skin changes, and abnormal blood fats increasing the risk.

Some drugs can cause serious side effects like heart issues and nervous system problems, but certain drugs for Parkinson's and overactive bladder may be safer, though they still have some common side effects.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Dutasteride may protect the brain in early Parkinson's disease.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Charnoly bodies could be a marker for cell damage, and certain nutrients and proteins might prevent them, potentially helping with brain diseases and cancer.

Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

New method uses hair follicle cells to estimate human body clock phase, potentially improving sleep disorder diagnosis.

Disrupting natural body clocks increases the risk of developing type 2 diabetes.

Healthy diet and exercise are important for women with PCOS to manage weight and metabolic issues, and supplements like omega-3, vitamin D, and inositol may help.

Fluconazole might be a new treatment for a type of diabetes that affects water balance in the body.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

Acanthosis nigricans in teenage girls with PCOS is a sign of obesity, not insulin resistance or glucose intolerance.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.

Anovulatory PCOS patients are younger with longer cycles and higher blood pressure and hormone levels.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.