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RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Skin fat helps with body temperature control and has other active roles in health.

Turing patterns are now recognized as important in developmental biology.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.