research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
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research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures
A blood pressure drug, diltiazem, may also help treat influenza.
research Two-Ligand Priming Mechanism for Potentiated Phosphoinositide Synthesis Is an Evolutionarily Conserved Feature of Sec14-Like Phosphatidylinositol and Phosphatidylcholine Exchange Proteins
A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.
research Beyond Counting Sheep: Exploring the Link Between Polycystic Ovary Syndrome and Sleep Health
PCOS often leads to sleep problems, especially obstructive sleep apnea, affecting overall health.
research The 5α-Reductase Inhibitor Finasteride Exerts Neuroprotection Against Ischemic Brain Injury in Aged Male Rats
Finasteride helps protect brain in old male rats.
research Alopecia Areata: Understanding and Treatment
Alopecia areata's causes are unclear, treatments exist but relapses are common.
research Female Sexual Dysfunction: Prevalence, Causes, and Treatments
Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Incidence of Alopecia from Endocrine Therapies in Cancer
Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.