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The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

A patient with Rothmund-Thomson syndrome showed skin changes, hair loss, and dental defects but no cataracts or skeletal issues.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Nearly half of children with primary immunodeficiency disorders showed skin problems, often as the first sign of their condition.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

The document concludes that various dermatological treatments and drugs can cause skin reactions and side effects.

The document is a detailed medical reference on skin and genetic disorders.

The document is a detailed guide on skin conditions and treatments for dermatologists.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.

DAVID syndrome is a condition with immune system and hormone deficiencies, needing early diagnosis to avoid serious complications.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Isotretinoin at a low dose for three months does not significantly affect hair growth.