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Two siblings have a rare genetic condition causing curly, coarse hair.

Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.

Early skin biopsy helps diagnose and manage severe skin conditions in babies.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Some medicinal plants can help heal wounds and may lead to new treatments.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.