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      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

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      community Breezula 6 Month Topline Phase III Results Released

      in Research/Science  138 upvotes 1 day ago
      Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.

      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 1 month ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community How many years can we expect PP405 to be on the market

      in Product  12 upvotes 3 months ago
      PP405 is expected to be on the market between 2027 and 2030, with phase 3 trials starting in 2026. There is skepticism about its fast-tracking due to its cosmetic nature, and it may appear on the gray market sooner.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 5 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.