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GlossaryPostmenopausal

stage after 12 months without a menstrual period

Postmenopausal refers to the stage in a woman's life that occurs after she has experienced 12 consecutive months without a menstrual period, marking the end of her reproductive years. This phase typically begins in women between the ages of 45 and 55 and is characterized by a decrease in the production of hormones such as estrogen and progesterone, which can lead to various physiological changes and symptoms, including hot flashes, osteoporosis, and changes in hair and skin.

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research Stromal Cells of the Human Postmenopausal Ovary Display a Distinctive Biochemical and Molecular Phenotype

June 2003 in “Obstetrical & Gynecological Survey”

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Discriminating Between Virilizing Ovary Tumors and Ovary Hyperthecosis in Postmenopausal Women: Clinical Data, Hormonal Profiles, and Imaging Studies

research Discriminating Between Virilizing Ovary Tumors and Ovary Hyperthecosis in Postmenopausal Women: Clinical Data, Hormonal Profiles, and Imaging Studies

27 citations, April 2017 in “European journal of endocrinology”

The research found that MRI and certain hormone levels can help tell apart ovarian tumors from hyperthecosis in postmenopausal women, but tissue analysis is still needed for a definite diagnosis.

research Approach to Investigation of Hyperandrogenism in a Postmenopausal Woman

November 2022 in “The Journal of Clinical Endocrinology and Metabolism”

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

research Bilateral Leydig Cell Hyperplasia: A Rare Cause of Postmenopausal Hirsutism

1 citations, February 2022 in “Case reports in endocrinology”

An unusual growth of Leydig cells in a woman's ovaries caused her excessive hair growth, which was treated successfully with surgery.

research Gonadotropin-Releasing Hormone Agonist Treatment in Postmenopausal Women with Hyperandrogenism of Ovarian Origin

36 citations, May 2011 in “The Journal of Clinical Endocrinology & Metabolism”

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

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community Losing Hair on Dutasteride? You might have LPP

in Research/Science 99 upvotes 1 month ago

Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 2 months ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 8 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community 24 y/o woman diagnosed with AGA today. Scared and confused.

8 upvotes 8 years ago

A 24-year-old woman being diagnosed with androgenic alopecia (AGA) who is scared and confused about her hair loss, and the treatment options of Minoxidil, finasteride, RU58841, spironolactone, and possibly a biopsy.

community 9 months of minoxidil , finasteride, spironolactone, estradiol

in Progress Pictures 59 upvotes 9 months ago

User shared progress pictures after 9 months of using minoxidil, finasteride, spironolactone, and estradiol for hair loss. Significant regrowth was noted, especially after starting estradiol.

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