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research Three-dimensional imaging for facial vitiligo: Results from a phase 2 randomized controlled trial investigating upadacitinib in patients with vitiligo

January 2026 in “Journal of Investigative Dermatology”

This study found that 3D imaging may serve as a promising tool for objectively evaluating facial vitiligo repigmentation after treatment with upadacitinib.

research 62823 Optimization of deuruxolitinib dosing in adult patients with alopecia areata: Results from a randomized, parallel-group, multicenter, Phase 2 trial

4 citations , September 2025 in “Journal of the American Academy of Dermatology”

The trial helped find the best dose of deuruxolitinib for treating alopecia areata.

Health-Related Quality of Life in Mild-Moderate Patchy Alopecia Areata: Results from the First Controlled Phase 2 Clinical Trial with STS01 (Dithranol/ProSilic) and Future Challenges

research Health-related quality of life in mild-moderate patchy alopecia areata: Results from the first controlled Phase 2 clinical trial in this population with STS01 (dithranol/ProSilic) and challenges for the future

April 2026 in “medRxiv”

In a phase 2 trial, researchers tested a topical formulation for alopecia areata and found significant hair regrowth with the treatment, but these improvements did not lead to substantial enhancements in health-related quality of life.

research Efficacy and safety of deuruxolitinib, an oral selective Janus kinase 1/2 inhibitor, in adults with alopecia areata: Results from the THRIVE-AA2 Phase 3, randomized, double-blind, controlled trial

2 citations , November 2025 in “Journal of the American Academy of Dermatology”

In this randomized, placebo-controlled trial, adults with severe chronic alopecia areata who received deuruxolitinib showed significant hair regrowth compared to placebo over 24 weeks, and the treatment was generally well-tolerated, though long-term effects remain unexamined.

research Small cell lung cancer: Results of a phase II study of 1,2,4 triglycidylurazol

6 citations , May 1986 in “Cancer Chemotherapy and Pharmacology”

The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.

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community GT20029 Phase 2 results are out

in Treatment 60 upvotes 9 months ago

GT20029 shows promising results for hair loss treatment, with potential approval in China by 2026 or 2027, but U.S. approval may take longer. It could serve as an alternative to finasteride, with a potentially better side effect profile.

community VDPHL01 phase-2/3 results comparison

in Research/Science 128 upvotes 4 months ago

The conversation discusses hair loss treatments, focusing on a new slow-release oral minoxidil compared to topical minoxidil and finasteride. The results show that twice-daily dosing of the new treatment is slightly more effective than once-daily, but concerns about cost, side effects, and the accuracy of reported results remain.

community GT20029 Big Phase 2 Update Results!

53 upvotes 9 months ago

GT20029 showed promising results for hair growth in a Phase II trial, with the 1.0% twice-weekly regimen being the most effective. Some users expressed skepticism and humor about the product's effects and market availability.

community It's the year 2050 and we are still waiting for Pelage to release the full phase 2 results of PP405 and start phase 3.

34 upvotes 7 months ago

Pelage plans to release phase 2 results and start phase 3 trials for PP405 in 2050, but skepticism remains due to past delays and unfulfilled promises. Users express frustration over the lack of progress in hair loss treatments, mentioning Minoxidil, finasteride, RU58841, CB-03-01, and Fluridil.

community TDM-105795 phase 2 results are in!

27 upvotes 2 years ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

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Learn

10 / 33 results

learn Scalp Micropigmentation

How long does Scalp Micropigmentation last, and does it need touch-ups over time? Scalp micropigmentation lasts 2 to 8 years and requires touch-ups every 1 to 5 years.

learn Hair Transplant

How long does a hair transplant procedure take? A hair transplant procedure typically takes 4 to 8 hours.

learn Fluridil

How long does it take to see results with Fluridil in progressive hair loss? No published study measures how long fluridil takes to show a visible change; the single double-blind trial (43 men, 2% fluridil) reported a rise in the proportion of hairs in the growth phase at three and nine months, and community reports describe stabilization rather than regrowth.

learn Bimatoprost

Can a lash-growth serum like bimatoprost actually work for your scalp? Bimatoprost (Latisse) is approved for eyelashes, not the scalp; two Allergan phase 2 trials in men with androgenetic alopecia posted results to ClinicalTrials.gov but were never published in a peer-reviewed journal, so scalp use remains off-label and experimental.

learn HMI-115

HMI-115: Frequently Asked Questions About Hair Loss Treatment HMI-115 is an investigational anti-prolactin-receptor antibody being trialled for androgenetic alopecia. It is not approved anywhere; its hair-loss evidence is a 16-person Phase 1b announced only by press release, plus a completed 192-man Phase 2 in China whose results are not yet published.

learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Epidermal Growth Factor

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