May 2005 in “Zhonghua chuangshang guke zazhi” This study found that human hair keratin bridges effectively induced nerve regeneration and demonstrated good biocompatibility and controlled degradation when used in rats with peripheral nerve defects.
January 2005 in “Zhonghua chuangshang guke zazhi” This study found that human hair keratin can effectively induce peripheral nerve regeneration in rats, showing good biocompatibility and a controllable degradation rate when used as a scaffold material.
January 2007 in “The FASEB journal” In this study, keratin hydrogels derived from human hair were found to significantly enhance nerve regeneration in a mouse model, acting effectively as scaffolds by influencing Schwann cell behavior.
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May 2026 in “Frontiers in Cell and Developmental Biology” This review explores the potential of neuro-driven hydrogels for skin and nerve regeneration, integrating biochemical cues and advanced technologies like AI for personalized wound healing, but notes the need for further validation and trials before clinical use.
This review summarizes the current applications and mechanisms of self-assembled peptide hydrogels in promoting skin, bone, and nerve regeneration, highlighting their potential due to their biocompatibility and supportive role in tissue healing.