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Bioinformatics Analysis of Genes Associated with Patchy-Type Alopecia Areata: CD2 May Be a New Therapeutic Target

research Bioinformatics analysis of genes associated with the patchy-type alopecia areata: CD2 may be a new therapeutic target

4 citations , September 2019 in “Biomedical Papers/Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic”

This study found that CD2 could be a potential new therapeutic target for treating patchy-type alopecia areata, suggesting the need for further research into its role.

An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis

research An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis

130 citations , February 2018 in “Journal of Investigative Dermatology”

This study found that tofacitinib led to ≥50% hair regrowth in eight out of twelve patients with moderate to severe alopecia areata, suggesting a potential benefit for using JAK inhibitors in treating this condition.

research Evaluation of Intralesional Triamcinolone Acetonide and Platelet‐Rich Plasma Therapy in Patients With Mild Patch‐Type Alopecia Areata

August 2026 in “Journal of Cosmetic Dermatology”

This study found that platelet-rich plasma showed similar efficacy to intralesional triamcinolone acetonide for treating mild patch-type alopecia areata, offering a potential alternative with fewer steroid-related side effects.

research Vitamin D levels and their relationship with the type of involvement in alopecia areata patients

May 2024 in “Journal of Pakistan Association of Dermatologists”

This study observed no statistically significant relationship between vitamin D levels and alopecia areata, including different types of the disease, suggesting vitamin D may not play a central role in its development or extent among a sample of adults.

research LB1034 Meta-analysis of scalp transcriptome defines alopecia areata subtypes and molecular response to four (4) treatments with jak inhibiting properties

July 2024 in “Journal of Investigative Dermatology”

JAK inhibitors improve hair growth in alopecia areata, especially in patchy types.

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Learn

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learn Baicapil

Struggling with patchy hair loss like alopecia areata? Baicapil might help by reducing inflammation and reactivating growth. There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts, in people with androgenetic-type hair loss rather than autoimmune patchy hair loss.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Overview

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

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Community Join

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community Losing hair without the white bulb, Tressless GPT's Response. Do you guys agree?

4 upvotes 1 year ago

Hair loss without a white bulb may indicate mechanical damage, anagen effluvium, alopecia areata, or traction alopecia. Seeking a specialist is recommended, but access can be difficult in smaller areas.

community Insane shed 3 months on Fin + Min Oral

88 upvotes 3 months ago

The user experienced severe hair shedding after starting oral Minoxidil and Finasteride, possibly due to stress from a breakup. Many suggest the shedding resembles alopecia areata and recommend seeing a doctor immediately.

community Hairloss all over body and head

4 upvotes 8 months ago

A 25-year-old experiencing hair thinning all over the body and head, despite using minoxidil and having low vitamin D levels, is advised to seek a second opinion from a dermatologist specializing in hair loss. The likely diagnosis is diffuse alopecia areata, which may require treatment with a JAK inhibitor.

community 30 Female, a month into 5% Minoxidil - is this normal?

28 upvotes 1 year ago

A 30-year-old woman experiencing rapid hair loss is using 5% Minoxidil, Saw Palmetto, vitamins, and Nizoral, but is advised to see a dermatologist as her symptoms may indicate a condition other than androgenetic alopecia, such as alopecia areata or a thyroid issue. Many suggest a biopsy and blood tests to determine the underlying cause.

community Dutasteride has been nuking me

in Finasteride/Dutasteride 156 upvotes 10 months ago

The user experienced significant hair loss after 9 months of using 0.5mg dutasteride and oral minoxidil, possibly due to alopecia areata. It is advised to consult a doctor for accurate diagnosis and treatment, as dutasteride and finasteride may not be effective.

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