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This study observed that the development of the pars intermedia in long-tailed macaques is closely associated with changes in skin pigmentation during pre- and postnatal periods through melanocyte-stimulating hormone and ACTH activity.

This study reported that horses with pituitary pars intermedia dysfunction had improved coat condition, advanced shedding, and better quality of life when treated with blue light masks.

This study found that pimozide, d-butaclamol, and pituitary pars intermedia grafts darken hair color in agouti C3H Avy mice, suggesting dopaminergic inhibition influences peptide-controlled hair color cycling.

This review discusses how skin lesions and haircoat changes in adult horses can indicate systemic diseases, emphasizing the need for veterinary evaluation, and reports no new clinical findings.

This source explains that Equine Cushing’s disease, or PPID, in horses is due to the degeneration of brain cells producing dopamine, leading to elevated cortisol levels and characteristic symptoms; it outlines diagnosis methods and emphasizes life-long pergolide treatment to manage the condition.