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research Structural Features and Sites of Expression of a New Murine 65 kD and 48 kD Hair-Related Keratin Pair, Associated with a Special Type of Parakeratotic Epithelial Differentiation

28 citations , August 1992 in “Differentiation”

A new pair of mouse keratins, 65 kD and 48 kD, are found in specific skin areas and are linked to a unique skin differentiation type.

research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle

87 citations , July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

research Characterization of a 300 Kbp Region of Human DNA Containing the Type II Hair Keratin Gene Domain

77 citations , March 2000 in “Journal of Investigative Dermatology”

The research identified six functional hair keratin genes and four pseudogenes, providing insights into hair formation and gene organization.

research Sequence and Expression of Human Hair Keratin Genes

19 citations , July 1994 in “Journal of Dermatological Science”

Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.

research Existence of Trichohyalin-Keratohyalin Hybrid Granules: Co-Localization of Two Major Intermediate Filament-Associated Proteins in Non-Follicular Epithelia

54 citations , November 1994 in “Differentiation”

Trichohyalin is found in non-hair tissues and works with filaggrin in certain skin areas and conditions.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.