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    GlossaryAnalgesics (Painkillers)

    medications that relieve pain without causing unconsciousness

    Analgesics, commonly known as painkillers or pain relievers, are medications designed to relieve pain without causing the loss of consciousness. They work by blocking pain signals from reaching the brain or by interfering with the brain's interpretation of those signals. Examples include over-the-counter options like ibuprofen and acetaminophen, as well as prescription medications such as opioids.

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      community Painkillers May Block Minoxidil

      in Research/Science  12 upvotes 2 weeks ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 month ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.