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    GlossaryAnalgesics (Painkillers)

    medications that relieve pain without causing unconsciousness

    Analgesics, commonly known as painkillers or pain relievers, are medications designed to relieve pain without causing the loss of consciousness. They work by blocking pain signals from reaching the brain or by interfering with the brain's interpretation of those signals. Examples include over-the-counter options like ibuprofen and acetaminophen, as well as prescription medications such as opioids.

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      community Painkillers May Block Minoxidil

      in Research/Science  13 upvotes 1 month ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community I bought 150€ worth of Avodart for nothing

      in Finasteride/Dutasteride  18 upvotes 2 weeks ago
      Dutasteride capsules were exposed to heat and humidity, causing them to soften, and the user considered replacing them with new ones from a local pharmacy. Suggestions included alternating between old and new capsules, storing them properly, and using them topically with Minoxidil, though the user decided to wait and see the effects of Dutasteride first.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 2 months ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.