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GlossaryOxidative Phosphorylation (OXPHOS)

process producing ATP in mitochondria using electron transport chain

Oxidative phosphorylation (OXPHOS) is a process that occurs in the mitochondria of cells, where energy from nutrients is used to produce ATP, the primary energy currency of the cell. This process involves the transfer of electrons through a series of proteins known as the electron transport chain, ultimately leading to the production of ATP through the enzyme ATP synthase.

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research Metabolic Teamwork in the Stem Cell Niche

14 citations, May 2017 in “Cell metabolism”

Paneth cells and intestinal stem cells work together metabolically for stem cell function and regeneration.

research Type 2-Mediated Oxidative Reprogramming Promotes Macrophage Transition into Repair Mode for Wound Healing

April 2023 in “Journal of Investigative Dermatology”

Type 2 inflammation helps wound healing by switching immune cells to repair mode.

research Reversing Wrinkled Skin and Hair Loss in Mice by Restoring Mitochondrial Function

74 citations, June 2018 in “Cell death and disease”

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Transient Mitochondrial DNA Double Strand Breaks in Mice Cause Accelerated Aging Phenotypes in a ROS-Dependent but p53/p21-Independent Manner

research Transient Mitochondrial DNA Double Strand Breaks in Mice Cause Accelerated Aging Phenotypes in a ROS-Dependent but p53/p21-Independent Manner

42 citations, December 2016 in “Cell Death & Differentiation”

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

research A Novel and Safe Small Molecule Enhances Hair Follicle Regeneration by Facilitating Metabolic Reprogramming

19 citations, December 2018 in “Experimental and Molecular Medicine”

Small molecule IM boosts hair growth by changing stem cell metabolism.

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community 2Y 5M on dut, ask me anything

in Finasteride/Dutasteride 130 upvotes 1 month ago

A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.