February 2026 in “Small Ruminant Research” This study on sheep coat type and fiber composition reveals that the IRF2BP2 gene, specifically the asEIF2S2 insertion and T7068586C SNP, plays a crucial role in determining fleece structure. Analyzing 692 ewes from various breeds, researchers found that the asEIF2S2 insertion is fixed in single-coated breeds and significantly influences fiber traits, increasing the non-medullated fiber ratio (NMFR) and decreasing hair fiber diameter (HFD). The T7068586C SNP, present in double-coated breeds, also affects NMFR and HFD. The optimal genotype combination, ++/CC, results in the highest NMFR and finest fibers, making it a valuable tool for improving fleece quality through marker-assisted selection. These findings provide new insights into the genetic basis of sheep fleece variation.
31 citations
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October 2016 in “PLoS ONE” The ubiquitin-mediated proteolysis pathway is crucial for hair follicle development in cashmere goats.
27 citations
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January 2010 in “Animal” South American camelids should be sheared early, fleece type affects fiber quality, and the S/P follicle ratio doesn't distinguish between Bolivian llama genotypes.
48 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.
18 citations
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November 2010 in “Journal of morphology” Antler velvet hair and body hair of red deer have different structures that help with protection and insulation.