April 2016 in “Journal of Investigative Dermatology” This study found that the CD301b-expressing subpopulation of macrophages plays a crucial role in promoting reparative processes during the mid-stage of skin wound healing in a mouse model.
March 2026 in “Skin Appendage Disorders” This study identified CD28, GZMB, and CD1C as key immune regulators in alopecia areata, highlighting CD28 as a potential therapeutic target with a promising safety profile, using a proteome-anchored multi-omics approach to uncover actionable targets for this autoimmune hair-loss disorder.
April 2023 in “Journal of Investigative Dermatology” This study identified distinct myeloid subsets in the scalp of men with androgenetic alopecia, potentially revealing new drug targets for treatment.
23 citations
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January 2024 in “Journal of Investigative Dermatology” In this study, researchers used advanced RNA sequencing techniques to discover that communication between specific fibroblast and myeloid cell populations may play a role in acne keloidalis, and found that corticosteroid injections could significantly reduce disease activity and gene expression related to these cells.
1 citations
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April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that wounding in skin induces significant fibroblast heterogeneity and recruits myeloid cells, which contribute to adipocyte regeneration in mice.