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GlossaryMelatonin Receptor 2 (MTNR1B)

protein that binds melatonin to regulate sleep-wake cycles

Melatonin Receptor 2 (MT2) is a protein found in the body that binds to melatonin, a hormone that regulates sleep-wake cycles. This receptor plays a crucial role in various physiological processes, including circadian rhythm regulation and potentially influencing mood and immune function. Understanding MT2 is important for developing treatments for sleep disorders and other conditions related to the body's internal clock.

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research Melatonin Increases Growth Properties in Human Dermal Papilla Spheroids by Activating AKT/GSK3β/β-Catenin Signaling Pathway

4 citations , May 2022 in “PeerJ”

Melatonin may help hair growth by affecting cell growth and hair-related signaling pathways.

research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions

506 citations , January 2012 in “Molecular and Cellular Endocrinology”

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

research Is Polycystic Ovary Syndrome a Sexual Conflict? A Review

21 citations , February 2016 in “Reproductive Biomedicine Online”

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

research Disturbance of the Circadian System in Shift Work and Its Health Impact

103 citations , December 2021 in “Journal of biological rhythms”

Shift work disrupts the body's natural clock, leading to health problems.

research Melatonin in Dermatologic Allergic Diseases and Other Skin Conditions: Current Trends and Reports

1 citations , February 2023 in “International Journal of Molecular Sciences”

Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.

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