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GlossaryMonolayer Culture

cells grown in a single layer on a flat surface

Monolayer Culture, also known as Monolayer Cell Culture, is a laboratory technique where cells are grown in a single layer on a flat surface, such as a petri dish or a flask. This method allows researchers to study cell behavior, interactions, and responses to various treatments in a controlled environment, making it a fundamental tool in cell biology and medical research.

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Effects of 1α,25-Dihydroxy-Vitamin D3 and Calcipotriol on Organotypic Cultures of Outer Root Sheath Cells: A Potential Model to Evaluate Antipsoriatic Drugs

research Effects of 1α,25-Dihydroxy-Vitamin D3 and Calcipotriol on Organotypic Cultures of Outer Root Sheath Cells: A Potential Model to Evaluate Antipsoriatic Drugs

10 citations, October 1993 in “Archives of dermatological research”

Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.

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December 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

Scientists found a new method using 3D cell cultures to grow human hair which may improve hair restoration treatments.

research Inhibitory Effects of bFGF, VEGF, and Minoxidil on Collagen Synthesis by Cultured Hair Dermal Papilla Cells

23 citations, July 1996 in “Archives of Dermatological Research”

bFGF, VEGF, and minoxidil decrease collagen production in hair cells, possibly affecting hair growth.

Involucrin, But Not Filaggrin and Kdap mRNA, Expression Is Downregulated in 3-D Cultures of Intact Rat Hair Bulbs After Calcium Stimulation

research Involucrin, But Not Filaggrin and Kdap mRNA, Expression Is Downregulated in 3-D Cultures of Intact Rat Hair Bulbs After Calcium Stimulation

3 citations, July 2011 in “Folia Histochemica et Cytobiologica”

Calcium reduces involucrin in rat hair bulbs but doesn't affect filaggrin and Kdap.

research Novel In Vitro Culture Condition Improves the Stemness of Human Dermal Stem/Progenitor Cells

18 citations, November 2013 in “Molecules and Cells”

New culture method keeps human skin stem cells more stem-like.

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