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research Consensus on the Use of Oral Isotretinoin in Dermatology - Brazilian Society of Dermatology

22 citations , October 2020 in “Anais Brasileiros de Dermatologia”

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

A Simple Decision Tree for Identifying Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation

research A Simple Decision Tree for Identifying Early Oral Drug Candidates With Likely Pharmacokinetic Nonlinearity by Intestinal CYP3A Saturation

November 2020 in “Journal of Pharmaceutical Sciences”

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Simultaneous Target-Mediated Drug Disposition-Pharmacodynamic Modeling of Finasteride and Dutasteride: Impact of Target Binding and Turnover on Non-Linear Pharmacokinetics

research Simultaneous Target-Mediated Drug Disposition-Pharmacodynamic Modeling of Finasteride and Dutasteride: Impact of Target Binding and Turnover on Non-Linear Pharmacokinetics

December 2025 in “The AAPS Journal”

Finasteride and dutasteride's effects are mainly due to target binding saturation and slow enzyme turnover.

Efficacy of Topical Minoxidil in Enhancing Beard Growth in Transgender Individuals Assigned Female at Birth on Gender Affirming Hormone Therapy

research Efficacy of Topical Minoxidil in Enhancing Beard Growth in Transgender Individuals Assigned Female at Birth on Gender Affirming Hormone Therapy

April 2024 in “Journal of endocrinological investigation”

Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.

research Considerations in Genetic Counseling of Transgender Patients: Cultural Competencies and Altered Disease Risk Profiles

17 citations , December 2020 in “Journal of Genetic Counseling”

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

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community My friend is so terrified of balding, he started microdosing estrogen…

in Treatment 1508 upvotes 3 weeks ago

A person is microdosing estrogen for hair loss after finasteride and dutasteride failed, risking feminizing effects. Alternatives like minoxidil, RU58841, or hair transplants are suggested.

community 3 months Min + Microdosing Fin

in Progress Pictures 23 upvotes 1 year ago

The user experienced significant hair growth over three months using topical Minoxidil, microdosing Finasteride, microneedling, and ketoconazole shampoo. They also use Toppik hair fibers and Aveda hair thickening tonic for styling.

community A Nuanced Look at Microdosing Topical Finasteride

in Finasteride/Dutasteride 87 upvotes 2 years ago

The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

community Ultimate DHT/finasteride microdosing graph to replace the commonly one referenced on forums

in Finasteride/Dutasteride 206 upvotes 5 years ago

Hair loss treatments, specifically, discussing the effectiveness and side effects of finasteride, minoxidil, and RU58841 in various microdoses. It also includes an updated graph which provides information on how different doses affect DHT levels, scalp skin and serum androgen levels, as well as hair count.

community Minimal dose of topical minioxidil for microdosing finisteride 0.0025

in Research/Science 2 upvotes 1 year ago

Using a microdose of finasteride on the scalp with minoxidil as a carrier may have positive effects with minimal side effects. The user is also considering the effects of sulforaphane or broccoli sprouts on hair loss.

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