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Hirsutism and the Variable Response of the Pilosebaceous Unit to Androgens

research Hirsutism and the Variable Response of the Pilosebaceous Unit to Androgen

56 citations , August 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

This review discusses the complex interaction between androgens and hair follicle biology, highlighting the need for a better understanding to improve hirsutism treatments, but reports no new results.

research Traumatic Alopecia in Trichotillomania: a Pathogenic Interpretation of Histologic Lesions in the Pilosebaceous Unit^*

37 citations , April 1977 in “Journal of Cutaneous Pathology”

This study found that specific histologic features in skin biopsies can help support a diagnosis of traumatic alopecia (trichotillomania), but not all markers are distinct to the condition.

research Effects of anabolic-androgenic steroids on the pilosebaceous unit.

16 citations , August 1992 in “PubMed”

In this study, examination of skin biopsies from individuals using anabolic-androgenic steroids revealed significant enlargement of sebaceous glands and associated increases in skin lipids and Propionibacteria acnes.

Confocal Microscopy and Optical Coherence Tomography of Inflammatory Skin Diseases in Hairs and Pilosebaceous Units: A Systematic Review

research Confocal microscopy and optical coherence tomography of inflammatory skin diseases in hairs and pilosebaceous units: A systematic review

May 2023 in “Experimental Dermatology”

This study found that both reflectance confocal microscopy and optical coherence tomography can visualize detailed hair follicle abnormalities in various skin disorders, but larger, higher-quality studies are needed for clinical implementation.

research Hair loss in adult females: A clinical and trichoscopic study

January 2021 in “International journal of dermatology, venereology and leprosy sciences”

This study found that trichoscopy is a valuable diagnostic tool for identifying hair loss patterns in women and can help avoid scalp biopsies in unclear cases.

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Community Join

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community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

59 upvotes 5 months ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

community Supposedly dairy contains precursors to DHT that are already 5a-reduced and convert to DHT independent of 5a-reductase inhibition

26 upvotes 5 months ago

Dairy may contain DHT precursors that could affect hair loss and prostate health, with some users noting reduced hair shedding after eliminating dairy. Individual responses to dairy and DHT blockers vary, with some attributing hair health to diet changes and others seeing no impact.

community Phase II topical dut study - outperforms oral fin with a minor DHT reduction

in Research/Science 61 upvotes 7 months ago

Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.

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