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    Glossary Inhibitors

    substances that slow or prevent specific biological processes

    Inhibitors are substances that slow down or prevent specific chemical reactions or biological processes. In the context of hair and alopecia, inhibitors can target enzymes or pathways that contribute to hair loss, potentially offering therapeutic benefits by halting or reversing the condition.

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    1. Baricitinib JAK inhibitor pill used for severe alopecia areata
    2. Tofacitinib JAK inhibitor pill, an immune-system drug
    3. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    4. Dutasteride 5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride
    5. PP405 mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials