research Insights Learned from L457(3.43)R, an Activating Mutant of the Human Lutropin Receptor 17 citations , October 2006 in “Molecular and Cellular Endocrinology” The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
research Spontaneous Fertility in a Male Patient with Testotoxicosis Despite Suppression of FSH Levels 3 citations , February 2018 in “Human Reproduction” A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.