1 citations
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January 2004 in “Elsevier eBooks” This review discusses the complexities and challenges in treating polycystic ovarian syndrome and concludes that while lifestyle and insulin-sensitizing treatments show promise, randomized controlled trials are lacking.
53 citations
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January 2011 in “Diabetes” The study found that severe insulin resistance and premature diabetes are common in patients with PCNT genetic defects, primarily affecting those over four years old, while not impacting early insulin signaling in adipocytes.
3 citations
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June 2025 in “Drug Design Development and Therapy” This review highlights the role of disrupted glycolysis in exacerbating reproductive and metabolic abnormalities in PCOS and suggests that agents like metformin and resveratrol may help restore glycolytic balance and improve ovarian function.
49 citations
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May 2020 in “Frontiers in Public Health” Insulin resistance linked to obesity may increase COVID-19 severity.
February 2026 in “World Journal of Interdisciplinary Innovation Sciences” This systematic review found that cinnamon supplementation may modestly improve insulin sensitivity and potentially reduce hyperandrogenism in women with PCOS, but stresses the need for large-scale clinical trials.