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research Estrogen Monotherapy for Testosterone Suppression in Gender Diverse Patients

October 2024 in “Journal of the Endocrine Society”

This study retrospectively reviewed estrogen monotherapy for testosterone suppression in gender diverse individuals assigned male at birth, specifically focusing on transfeminine patients. Out of 10 patients aged 19-81, 7 transfeminine patients achieved testosterone suppression with serum estradiol levels over 100 pg/mL, using either injectable or transdermal estrogen formulations. Injectable formulations were more common among those who achieved suppression. The study suggests that estrogen monotherapy could be effective without anti-androgens, though the small sample size is a limitation. Further research is needed to explore its potential for simplifying treatment protocols.

research Androgen Insufficiency in Women: Diagnostic and Therapeutic Implications

59 citations, August 2004 in “Human Reproduction Update”

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

research Cross-Sex Hormone Therapy for Gender Dysphoria

21 citations, November 2014 in “Journal of Endocrinological Investigation”

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Effect of the Frequency of Injection on the Clinical Responses of Postmenopausal Women to Testosterone Enanthate with Estradiol Valerate

research Effect of the Frequency of Injection on the Clinical Responses of Postmenopausal Women to Testosterone Enanthate with Estradiol Valerate

May 1963 in “American journal of obstetrics and gynecology”

Injecting 2 ml of TEEV every 4 weeks is better because it has the same benefits but fewer side effects.

research Safety of Testosterone Treatment in Postmenopausal Women

81 citations, May 2007 in “Fertility and Sterility”

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

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community Found the solution tressbros - 1.5 years 2.5mg oral minox, 5mg finasteride, 8mg estradiol valerate (weekly)

in Transgender 591 upvotes 8 months ago

The conversation discusses a transgender individual's successful hair loss treatment over 1.5 years using 2.5mg oral minoxidil, 5mg finasteride, and 8mg weekly injectable estradiol valerate. Some users debate the appropriateness of this approach within the group's goals, while others support the individualized treatment and its additional benefits for transgender individuals.

community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

in Transgender 127 upvotes 10 months ago

A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

community What next after 2 years of fin and min?

in Progress Pictures 18 upvotes 6 months ago

The user has been using finasteride and minoxidil for hair loss for 2 years and started microneedling, now considering a hair transplant in Mexico. Suggestions include trying dutasteride, oral minoxidil, and various opinions on hair transplant locations and the user's current hair condition.

community How many mgs of zinc should I take while taking fin? I want to potentially offset side effects but not ruin the effectiveness of fin. I take .5 mg fin daily

in Chat 13 upvotes 2 years ago

A user asks about the appropriate zinc dosage to offset side effects while taking 0.5 mg of finasteride daily. Responses suggest zinc has a minor effect on hormones compared to finasteride.

community How to Keep Your Hair on Steroids

in Treatment 14 upvotes 3 weeks ago

To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

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