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GlossaryImmune Receptor

protein on immune cells that detects foreign substances

An immune receptor, also known as an immunoreceptor, is a protein found on the surface of immune cells, such as T cells and B cells. These receptors recognize and bind to specific antigens (foreign substances like bacteria or viruses), triggering an immune response to help the body fight off infections.

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research Molecular Mechanisms of Viral Oncogenesis in Humans

141 citations , August 2018 in “Nature Reviews Microbiology”

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

research Tregs: Where We Are and What Comes Next?

130 citations , November 2017 in “Frontiers in Immunology”

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

research Regulatory T Cells: The Many Faces of Foxp3

125 citations , September 2019 in “Journal of Clinical Immunology”

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

research Alopecia Areata: Animal Models Illuminate Autoimmune Pathogenesis and Novel Immunotherapeutic Strategies

82 citations , March 2016 in “Autoimmunity reviews”

Animal models have helped understand hair loss from alopecia areata and find new treatments.

research Replicative Stress, Stem Cells, and Aging

70 citations , March 2008 in “Mechanisms of Ageing and Development”

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

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