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GlossaryImmune Receptor

protein on immune cells that detects foreign substances

An immune receptor, also known as an immunoreceptor, is a protein found on the surface of immune cells, such as T cells and B cells. These receptors recognize and bind to specific antigens (foreign substances like bacteria or viruses), triggering an immune response to help the body fight off infections.

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research Molecular Mechanisms of Viral Oncogenesis in Humans

141 citations, August 2018 in “Nature Reviews Microbiology”

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

research Tregs: Where We Are and What Comes Next?

130 citations, November 2017 in “Frontiers in Immunology”

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

research Regulatory T Cells: The Many Faces of Foxp3

125 citations, September 2019 in “Journal of Clinical Immunology”

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

research Alopecia Areata: Animal Models Illuminate Autoimmune Pathogenesis and Novel Immunotherapeutic Strategies

82 citations, March 2016 in “Autoimmunity reviews”

Animal models have helped understand hair loss from alopecia areata and find new treatments.

research Replicative Stress, Stem Cells, and Aging

70 citations, March 2008 in “Mechanisms of Ageing and Development”

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

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