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GlossaryInterleukin-36 (IL36)

group of cytokines involved in immune system signaling and inflammation

Interleukin-36 (IL-36) is a group of cytokines, which are small proteins important for cell signaling in the immune system. These cytokines play a crucial role in inflammatory responses and are involved in the pathogenesis of various autoimmune and inflammatory diseases, such as psoriasis. IL-36 includes three agonists (IL-36α, IL-36β, and IL-36γ) and an antagonist (IL-36Ra), which together help regulate the body's immune response.

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research Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review

1 citations, June 2023 in “Genes”

Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.

research Modulating Embryonic Signaling Pathways Paves the Way for Regeneration in Wound Healing

February 2024 in “Frontiers in physiology”

Modifying certain signals in the body can help wounds heal without scars and regrow hair.

Dimethyl Fumarate Ameliorates Delayed Wound Healing Due to IL-36Ra Deficiency Through Inhibition of NET Formation and Oxidative Stress

research Dimethyl Fumarate Ameliorates Delayed Wound Healing Due to IL-36Ra Deficiency Through Inhibition of NET Formation and Oxidative Stress

April 2023 in “Journal of Investigative Dermatology”

Dimethyl fumarate speeds up wound healing in IL-36Ra deficient mice by reducing NET formation and oxidative stress.

research What's New in Dermatological Research?

2 citations, December 2011 in “Annales de Dermatologie et de Vénéréologie”

2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.

research Dermatologic Toxicities Associated with Chronic Gamma-Secretase Inhibitor Treatment for Desmoid Tumor

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.

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