January 1989 in “Side effects of drugs annual” This chapter reviews studies on the side effects of cytostatics and immunosuppressive drugs, detailing various toxicities such as cardiovascular, pulmonary, and neurotoxicity, but provides no new clinical results.
April 2022 in “Anti-cancer agents in medicinal chemistry” In this literature review, researchers compiled evidence on repurposed synthetic radioprotective agents, including metformin and simvastatin, that have demonstrated potential in mitigating the side effects of radiotherapy in cancer treatment.
10 citations
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January 1994 in “Advances in pharmacology” This review examines the role of topoisomerase-interacting drugs in cancer treatment and emphasizes the importance of understanding their mechanisms for clinical development, but it presents no new results.
9 citations
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April 2021 in “Evidence-based complementary and alternative medicine” This study found that Guilu Erxian Glue significantly alleviates various doxorubicin-induced side effects in mice, enhancing exercise capacity and reducing oxidative stress and inflammation.
August 2016 in “PolyPublie (École Polytechnique de Montréal)” This study observed early cardiac effects in young minipigs following high-dose doxorubicin chemotherapy, with a decrease in heart function and changes in cardiac MRI measurements compared to controls.