research The Abnormal, Mislocalized HR BMH Protein Associates with Members of the Protein Processing Machinery in the Cytoplasm
The mutant HR bmh protein mis-localizes in cells, affecting skin and hair development.
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5 / 1000+ resultsresearch The 'Bald Mill Hill' Mutation in the Mouse Is Associated with an Abnormal, Mislocalized HR BMH Protein
research Analysis of Hairless Gene Regulation and Identification of Affected Signaling Pathways in 'Bald Mill Hill' Mutants
The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.
research Characterization of Hairless (Hr) and FGF5 Genes Provides Insights into the Molecular Basis of Hair Loss in Cetaceans
Cetaceans lost hair due to changes in the Hr and FGF5 genes.
research A Novel Mutation in Hr Causes Abnormal Hair Follicle Morphogenesis in Hairpoor Mouse, an Animal Model for Marie Unna Hereditary Hypotrichosis
A new mutation in the Hr gene causes hair loss in mice, similar to a human hair disorder.
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5 / 64 resultscommunity This tells you if you're shedding or losing hair (along with other things like fibrosis)
High frequency ultrasonography and HR-MRI can help identify hair shedding causes like inflammation and fibrosis. The conversation discusses the potential of using these technologies to evaluate treatments like Verteporfin for hair regeneration.
community Have some questions about prescription I got from a trichologist
A trichologist prescribed Biotrade Sebomax HR Anti-Hair Loss Tonic, Spectral DNC-N Nanoxidil, Hairfollic Him/Man Vitamins, and Bosley MD DHT blocking supplements instead of finasteride due to potential risks at age 21. The user questions the legitimacy of the treatment and considers seeking a second opinion.
community A better treatment would be a localized 5ar inhibitor that breaks down when it enters blood or leaves hair follicle
The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic side effects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.
community Hair progress over 7 years (Oral fin 1mg + oral min 2.5mg + topical min 5% + micro-needling)
The user shared a 7-year hair progress journey, starting with occasional minoxidil use and later including a finasteride prescription, online prescriptions, and microneedling. Significant hair growth was achieved, but side effects led to a reduction in medication dosage.
community Do people still use microneedling?
Microneedling is still considered effective for hair growth, especially when combined with minoxidil, though it is time-consuming. Some users report significant success with consistent use, while others find it less popular due to the effort required compared to topical treatments alone.