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research Measurement of Steroid Hormones in Hair: an Analysis of Hormone Dynamics in Hair Follicles

January 2024 in “Institutional Repositories DataBase (IRDB)”

This study developed a method to measure local steroid hormone concentrations in hair, providing new insights into hormone dynamics associated with androgenetic alopecia.

research Cholesterol homeostasis: Links to hair follicle biology and hair disorders

25 citations , July 2019 in “Experimental Dermatology”

This review discusses the role of cholesterol homeostasis in hair follicle biology and its potential connections to various hair disorders, but it reports no new findings.

research Lecithin organogels as a potential phospholipid-structured system for topical drug delivery: A review

202 citations , June 2005 in “Aaps Pharmscitech”

This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.

research Sexually dimorphic sail feathers in the Mandarin duck as a model for lifelong developmental modulation

1 citations , October 2025 in “Scientific Reports”

This study investigated the Mandarin duck as a model for understanding lifelong developmental changes, finding that male sail feather morphogenesis involves a combination of local morphogenetic programs, epigenetic regulation, and hormonal cues, with increased female estrogen levels observed before the mating season.

research A volatile producing Bacillus subtilis strain from the rhizosphere of Haloxylon ammodendron promotes plant root development

October 2022 in “Research Square (Research Square)”

This study found that volatile compounds from Bacillus subtilis strain WM13-24 improved root development in Arabidopsis by influencing auxin signaling.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

121 upvotes 2 years ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community I asked ChatGPT about PP405, is everything correct here?

1 year ago

PP405 is a new topical drug that reactivates dormant hair follicle stem cells by inhibiting the MPC protein, shifting cell metabolism to glycolysis, and potentially regrowing hair even in bald areas. It differs from minoxidil and finasteride as it does not alter hormones or blood flow but instead targets cell metabolism.

community Sorry yall I cheated 😵‍💫 1 year fin + hrt

682 upvotes 9 months ago

Hair regrowth and gender transition using finasteride, estrogen, and spironolactone. Significant hair regrowth and personal transformation were achieved through hormone replacement therapy.

community I think we should all keep an eye out for Pelage PP405. February 2025 will be interesting.

118 upvotes 1 year ago

Pelage PP405 is a new hair loss treatment in trials, potentially reactivating dormant hair follicles without affecting hormones. Results are expected in February 2025, offering an alternative to minoxidil and finasteride.

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