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research Insertional mutation of the hairless locus on mouse Chromosome 14

19 citations , November 1993 in “Mammalian Genome”

This study reports that transgene insertion in homozygous transgenic mice causes irreversible hair loss and impaired immune function, linked to interruption of the hairless locus on Chromosome 14.

research A distinct gene close to the hairless locus on chromosome 8p underlies hereditary Marie Unna type hypotrichosis in a German family

36 citations , October 2000 in “British Journal of Dermatology”

This study identified a distinct gene near the hairless locus on chromosome 8p that is responsible for hereditary Marie Unna type hypotrichosis in a German family.

research The abnormal, mis-localizated HR bmh protein associates with members of the protein processing machinery in the cytoplasm

January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that the mutant hairless rhino bald protein in mice interacts with the vitamin D receptor but cannot repress its transactivation and shows abnormal cellular localization.

research An Australian family with macular dystrophy linked to autosomal recessive alopecia universalis

3 citations , February 2001 in “British journal of ophthalmology”

This case report presents a 28-year-old woman with alopecia universalis and macular dystrophy, highlighting a potential new linkage between these conditions without previously identified associated genes.

research 921 Generation of a new rodent model of scleroderma

April 2019 in “Journal of Investigative Dermatology”

Researchers created a new mouse model for studying scleroderma.

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community Reversed hairloss, 20 month update

3503 upvotes 1 year ago

A user successfully regrew hair over 20 months using oral dutasteride and minoxidil, with no significant side effects. They are satisfied with the results but may consider a hair transplant for more density.

community The "I just want hair until im 30" cope.

in Chat 220 upvotes 1 year ago

Participants want to maintain hair until at least age 30, using treatments like finasteride, dutasteride, and minoxidil. Hair loss remains a concern, with some considering hair transplants.

community Quitting kratom stopped my hairloss by 80%

in Research/Science 67 upvotes 2 years ago

Quitting kratom reduced hair loss by 80% for a 23-year-old male. Others discussed kratom's effects and potential side effects on hair health.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

community Before you feel down about your hairloss

27 upvotes 9 years ago

Hair loss can be distressing, but treatments like finasteride, minoxidil, and scalp micropigmentation can help manage it. Embrace self-improvement, focus on personal goals, and maintain a positive attitude despite hair loss challenges.

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